As I eagerly opened the repeat test results for two patients and me, I expected the salivary adrenal profile would demonstrate improved function in the form of healthier hormone levels. After all, the subjects in this initial testing were highly compliant and motivated patients. We dutifully took the supplement protocol laid out for four months, and we each had symptomatic improvement. It was not a slight but a significant reduction in fatigue, sleep problems, concentration difficulties, etc. There was every reason to expect the tests would confirm our success.

With great disappointment, I read the results for each of us that were nearly identical to the initial testing. No improvements were demonstrated by any of the tests. How could that be?


Three Lessons on Stress

The following afternoon, I was on the phone with my mentor, the late William Timmins, ND, who asked me the pivotal question: “What did the patients do to change their lifestyle during the four-month window?” I had no answer. Each of us had felt so much better on the supplements that we did not consider anything else. Dr. Timmins made it clear that unless there was a change in the overall stress stimulus, the HPA axis would not be significantly changed and the test results would be the same. He went on to review the principles of blood sugar control, quality sleep, and chronic inflammation and infection as profound drivers of the HPA axis.


1. Beyond Nutrition

That was when the first lightbulb went off for me. You see, up until that point, I was viewing stress as an adrenal issue: Provide nutrients to support the gland, and voilà, we should be on the road to recovery. The problem with this line of thinking is that stress manifests in the brain. We now know through decades of research that the adrenal glands secrete the cortisol and DHEA(S) measured in saliva, but the mechanisms controlling these hormones reside outside the glands. I began to understand the importance of encouraging patients to make lifestyle changes in order to improve the trajectory of their health.


2. Stress on the Mind

My second “aha” moment came about a year later when I had done everything I knew to help a patient with daily headaches. Over the course of six months, we were able to reduce the frequency and severity of the headaches, but they remained disruptive to his life, and he eventually fell off my schedule. About seven months after our last visit, he called my office to tell me he had not had a headache in over four months. When I asked him how he achieved this, he explained that he had resigned from his CEO position at a failing tech firm and had his last headache a week later. It was humbling for me to hear that.


3. Other Symptom Origins

My third—but certainly not last—teachable moment came when a 30-year-old mother of two young children came to me with profound fatigue. She related that her typical day consisted of waking up to make breakfast for her toddlers and then lying on the couch while they played in the living room. At lunchtime, she rose to make their meals and returned to the couch once again. When her husband came through the door in the evening, she went upstairs to bed. She had lived like this for about eight or twelve weeks. After CBC, CMP, and thyroid testing were normal, I sent her home with a salivary hormone test kit and explained that I wanted to see her adrenal axis function. The patient called three to four weeks later to say she never ran the test and no longer needed my help because her energy had returned. She had four root canals, three of which harbored abscesses, and after extractions and reworking of the remaining teeth, her energy had returned to about 80-90%.


Lifestyle Changes for Stress Management

Today, when reviewing the results of salivary hormones with patients, my care plan begins and ends with lifestyle. In fact, I give patients the SOS Patient Handbook when they get their at-home collection kits. I instruct them to read the entire handbook and implement its practices during the two-week wait for results. Those who do read and use its recommendations frequently tell me their symptoms improve. Those who do not receive their test results and a second encouragement to read the handbook and start with blood sugar control, sleep regulation and stress reduction prior to beginning the supplement protocols.

In instances when I took the shortcut and relied only on the supplements, we saw less-than-optimal results. By insisting that patients incorporate needed lifestyle changes, I have seen very few patients return to my office two weeks after starting supplement protocols with no improvement.


The Bottom Line

The cases above are only a small sample of the “tuition” I paid to become educated on the importance of a healthy lifestyle. I hope you will benefit from these anecdotes and make lifestyle a priority in your patients’ stress management care plans. You’ll see truly satisfying outcomes as a result.

Remember, always lead with lifestyle!



Christopher Mote, DO, DC, IFMCP earned his doctorate in osteopathy from the Chicago College of Osteopathic Medicine at Midwestern University. He earned his doctorate in chiropractic and Bachelor of Science in human biology from the National University of Health Sciences (NUHS) in Lombard, Illinois, and is certified in Functional Diagnostic Medicine. With a focus on addressing the root cause of health concerns, Dr. Mote specializes in the diagnosis and treatment of chronic health disorders.