Upcoming Webinar:

Is It the Adrenals or the Brain? Navigating HPA Axis Activation and Neurotransmitter Signaling

Christopher Mote, DO, DC


Stress, whether real or perceived, must first be translated into neurochemical signals before triggering the HPA axis. It is well-known that the brain regions responsible for interpreting perceived stress (amygdala, hippocampus, prefrontal cortex and hypothalamic PVN) are highly influenced by neurotransmitter signaling. The manifestations of HPA axis dysfunction caused by stress, such as feeling a loss of control, burnout-withdrawal and worry, overlap with those of both anxiety and depression. For this reason, it is often difficult to separate the diagnostic and treatment approaches for these patients.

Join Dr. Christopher Mote, ARK Stress Recovery Program Clinical Expert, as he discusses:

  • The Brain as the Primary Initiator and Perpetuator of the HPA Axis
  • How Chronic Stress Leads to Neurotransmitter Depletion and HPA Axis Dysfunction
  • Strategies to Support the HPA Axis and Address Neurotransmitter Imbalances



Christopher Mote, DO, DC

Christopher Mote, DO, DC, earned his doctorate in osteopathy from the Chicago College of Osteopathic Medicine at Midwestern University. He earned his doctorate in chiropractic and Bachelor of Science in human biology from the National University of Health Sciences (NUHS) in Lombard, Illinois, and is certified in Functional Diagnostic Medicine.

Dr. Mote also serves as the ARK Stress Recovery Program Clinical Expert at the Lifestyle Matrix Resource Center. With a focus on addressing the root cause of health concerns, Dr. Mote specializes in the diagnosis and treatment of chronic health disorders.

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