Is It the Adrenals or the Brain? Navigating HPA Axis Activation and Neurotransmitter Signaling
Christopher Mote, DO, DC
Stress, whether real or perceived, must first be translated into neurochemical signals before triggering the HPA axis. It is well-known that the brain regions responsible for interpreting perceived stress (amygdala, hippocampus, prefrontal cortex and hypothalamic PVN) are highly influenced by neurotransmitter signaling. The manifestations of HPA axis dysfunction caused by stress, such as feeling a loss of control, burnout-withdrawal and worry, overlap with those of both anxiety and depression. For this reason, it is often difficult to separate the diagnostic and treatment approaches for these patients.
Join Dr. Christopher Mote, ARK Stress Recovery Program Clinical Expert, as he discusses:
The Brain as the Primary Initiator and Perpetuator of the HPA Axis
How Chronic Stress Leads to Neurotransmitter Depletion and HPA Axis Dysfunction
Strategies to Support the HPA Axis and Address Neurotransmitter Imbalances